ChemInform Abstract: Nitrosation of 2-Aryl-1,1-dibromocyclopropanes: Synthesis of 3-Aryl-5-bromoisoxazoles
Autor: | Pavel A. Danilov, Aleksandr A. Vinogradov, Anna Yu. Gavrilova, Nikolai V. Zyk, S. N. Nikolaeva, Oksana B. Bondarenko |
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Rok vydání: | 2016 |
Předmět: | |
Zdroj: | ChemInform. 47 |
ISSN: | 0931-7597 |
Popis: | An efficient transformation of 2-aryl-1,1-dibromocyclopropanes under the action of sulfur trioxide activated nitrosyl chloride has been developed, providing a series of arylated 5-bromoisoxazoles with good yields. It is noteworthy that under the reported conditions the nitrosation–heterocyclization reaction proceeded with high regioselectivity leading exclusively to 3-aryl-5-bromoisoxazoles. |
Databáze: | OpenAIRE |
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