Novel Clinical mNGS-Based Machine Learning Model for Rapid Antimicrobial Susceptibility Testing of Acinetobacter baumannii

Autor: Xuejiao Hu, Yunhu Zhao, Peng Han, Suling Liu, Weijiang Liu, Cong Mai, Qianyun Deng, Jing Ren, Jiajie Luo, Fangyuan Chen, Xuefeng Jia, Jing Zhang, Guanhua Rao, Bing Gu
Rok vydání: 2023
Předmět:
Zdroj: Journal of Clinical Microbiology. 61
ISSN: 1098-660X
0095-1137
DOI: 10.1128/jcm.01805-22
Popis: Multidrug-resistant (MDR) bacteria are important public health problems. Antibiotic susceptibility testing (AST) currently uses time-consuming culture-based procedures, which cause treatment delays and increased mortality. We developed a machine learning model using Acinetobacter baumannii as an example to explore a fast AST approach using metagenomic next-generation sequencing (mNGS) data.
Databáze: OpenAIRE