Palladium-catalyzed cyclizative cross coupling of ynone oximes with 2-haloaryl N-acrylamides for isoxazolyl indoline bis-heterocycles

Autor:	Ramesh Kotipalli, Attunuri Nagireddy, Maddi Sridhar Reddy
Rok vydání:	2022
Předmět:	Organic Chemistry Physical and Theoretical Chemistry Biochemistry
Zdroj:	Organic & Biomolecular Chemistry. 20:2609-2614
ISSN:	1477-0539 1477-0520
DOI:	10.1039/d2ob00065b
Popis:	We demonstrated a dual-cyclizative coupling of ynone oxime ethers with acrylamides for the synthesis of isoxazolyl 2-oxindoles. The cascade is triggered by a palladium(ii)-catalyzed ynone oxime ether cyclization, and is completed by a Heck-type coupling.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c337bb7ff63ca9defde31dddbb10d882 https://doi.org/10.1039/d2ob00065b Zobrazit plný text záznamu