Using Image-Based Flow Cytometry to Assess Monocyte Oxidized LDL Phagocytosis Capacity

Autor: Andrea L. Henning, Adam S. Venable, Eric A. Prado, Brian K. McFarlin
Rok vydání: 2015
Předmět:
Zdroj: Imaging Flow Cytometry ISBN: 9781493933006
Popis: The examination of monocyte phagocytosis of modified lipoproteins is important to the understanding of plaque deposition and the development of atherosclerosis. Current methods lack the high-throughput image-based analysis capabilities, which may yield novel information concerning monocyte activity in disease processes. Specifically, this method identifies monocyte phagocytosis of oxidized LDL along with a change in adhesion molecules and scavenger receptors. Our laboratory is currently implementing this method as a means to study how acute dietary modifications alter risk of developing atherosclerosis.
Databáze: OpenAIRE