| Autor: |
Negussie Beyene, Amanda Mahoney, Amy Durgin, Alan Poling, Bart Weetjens, Maureen Jubitana, Timothy L. Edwards, Christophe Cox |
| Rok vydání: |
2013 |
| Předmět: |
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| Zdroj: |
The Psychological Record. 63:583-594 |
| ISSN: |
0033-2933 |
| DOI: |
10.11133/j.tpr.2013.63.3.012 |
| Popis: |
Pouched rats can detect Mycobacterium tuberculosis, which causes tuberculosis, in human sputum. Historically, a phosphate-buffered saline solution was added to sputum in the belief that doing so improved rats’ detection of M. tuberculosis, but no relevant data were available. Experiment 1 evaluated rats’ performance on samples with and without phosphate-buffered saline solution added. There was no difference in detection accuracy. Adding the solution slows sample processing and will not be done in future operational applications. Experiment 2 compared the performance of rats trained on sputum samples with low versus high concentrations of M. tuberculosis. Training on low-concentration samples improves sensitivity on that sample type. Unfortunately, it is impractical to arrange low-concentration training in the current operational setting, where the rats are used for the second-line screening of samples initially evaluated by microscopy. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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