Diagnosis of Neoplastic Changes by Magnifying Colonoscopy in a Patient with Cronkhite–Canada Syndrome: A Case Report
| Autor: | Kazutomo Togashi, Fumio Konishi, Hideo Nagai, Hirotake Satoh, Kazuya Sakuma |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Pathology
medicine.medical_specialty Adenoma medicine.diagnostic_test business.industry Colorectal cancer Gastroenterology Colonoscopy Sigmoid colon Histology medicine.disease digestive system diseases medicine.anatomical_structure Biopsy medicine Atypia Radiology Nuclear Medicine and imaging Cronkhite–Canada syndrome business |
| Zdroj: | Digestive Endoscopy. 12:255-258 |
| ISSN: | 1443-1661 0915-5635 |
| DOI: | 10.1046/j.1443-1661.2000.00062.x |
| Popis: | The authors described a typical case of Cronkhite–Canada syndrome, in which the terminal ileum and entire colorectum were meticulously observed by magnifying colonoscopy. Colonoscopy revealed a remarkably reddish and rough mucosa with small white spots in the right side of the colon, where there were a small number of sessile polyps measuring less than 10 mm in diameter. On magnified views, the pit pattern of these polyps consisted of slightly enlarged pits with an obvious widening of the pericryptal space, which were compatible with that of non-neoplastic change. Biopsy specimens showed histologically dilated glands without dysplastic changes. A large number of reddish, elliptic and sessile polyps were observed in the left side of the colon. The pit pattern and histology of these polyps were almost the same as those of the polyps in the right side. There were two small sessile polyps of a different type in the mid-transverse colon and in the sigmoid colon. These polyps were diagnosed as having neoplastic changes, according to the pit pattern diagnosis and the histology of both was adenoma with slight atypia. According to a review of the worldwide reports, a patient with Cronkhite–Canada syndrome has a high risk of developing colorectal carcinoma. Based on our experience, magnifying colonoscopy may be useful for identifying neoplastic changes in patients with Cronkhite–Canada syndrome. |
| Databáze: | OpenAIRE |
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