First synthesis of a new acetogenin of annonaceae, reticulatamol : Activated tin hydride with enhanced reducing ability

Autor:	Bui Chi Hieu, Christophe Chaboche, André Cavé, Bruno Figadère, B. Chappe, Vu Thi Tam
Rok vydání:	1994
Předmět:	chemistry.chemical_classification Ketone Organic Chemistry Iodide Total synthesis Biochemistry chemistry.chemical_compound chemistry Yield (chemistry) Drug Discovery Acetogenin Organic chemistry Chemoselectivity Enone Alkyl
Zdroj:	Tetrahedron Letters. 35:883-886
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(00)75989-2
Popis:	A new annonaceous acetogenin, reticulatamol 1, is described. In order to confirm its structure, its total synthesis has been performed, using as a key step a radical coupling reaction between an alkyl iodide and an enone, followed by an original reduction of the so obtained ketone to yield the desired natural product.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c31e76fb6c46c6c6983a65847dc353ba https://doi.org/10.1016/s0040-4039(00)75989-2 Zobrazit plný text záznamu