In vitro Antibacterial Efficacy of Bidens pilosa, Ageratum conyzoides and Ocimum suave Extracts against HIV/AIDS Patients’ Oral Bacteria in South-Western Uganda
Autor: | Steve Ogbonnia, Muhammad Ntale, Jennifer Chibuogwu Ebosie, Julius Kihdze Tanayen, Frederick Byarugaba, J.O.C. Ezeonwumelu, Keneth Iceland Kasozi, Onokiojare Ephraim Dafiewhare, Chukwudi Onyeka Okonkwo, Ezera Agwu, Ambrose Amamchukwu Akunne, Anthonia Shodunke |
---|---|
Rok vydání: | 2017 |
Předmět: |
0301 basic medicine
Aids patients biology Traditional medicine business.industry Ageratum conyzoides 030106 microbiology Antibacterial efficacy biology.organism_classification medicine.disease Ocimum 03 medical and health sciences Acquired immunodeficiency syndrome (AIDS) Interactive effects Bidens pilosa medicine business Bacteria |
Zdroj: | Pharmacology & Pharmacy. :306-323 |
ISSN: | 2157-9431 2157-9423 |
DOI: | 10.4236/pp.2017.89023 |
Popis: | The objective of the study was to determine the antibacterial efficacy of Bidens pilosa Aqueous (BPA), Bidens pilosa Ethanolic (BPE), Ageratum conyzoides Aqueous (ACA), Ageratum conyzoides Ethanolic (ACE), Ocimum suave Aqueous (OSA) and Ocimum suave Ethanolic (OSE) extracts on HIV/AIDS patients’ oral bacteria. Healthy green leaves of the plants were collected in Ishaka Uganda, processed and portions separately extracted with hot distilled water and cold ethanol. The susceptibility, MIC and MBC of each extract were determined using standard protocols. The bacteria had significant (p Bidens pilosa, Ageratum conyzoides and Ocimum suave on oral lesions of HIV/AIDS patients made by traditional healers and local people in South-Western Uganda. We recommend a detailed study of structural identities and activities of the active antibacterial principle(s) in these plants for possible new drug entities and verification of the interactive effects of the principle(s) with ARVs and cotrimoxazole used daily by HIV/AIDS patients. |
Databáze: | OpenAIRE |
Externí odkaz: |