Red-emitting, EtTP-5-based organic nanoprobes for two-photon imaging in 3D multicellular biological models
| Autor: | Nathalie M. Pinkerton, Valérie Lobjois, Matthew J. Bruzek, Céline Frongia, Frédéric Bolze, Robert K. Prud'homme, John E. Anthony, Brian K. Wilson, Stefan Chassaing |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Materials science
General Chemical Engineering Nanoparticle Nanotechnology 02 engineering and technology General Chemistry 010402 general chemistry 021001 nanoscience & nanotechnology Biocompatible material 01 natural sciences Fluorescence 0104 chemical sciences Flash (photography) Multicellular organism Two-photon excitation microscopy Multicellular spheroid 0210 nano-technology |
| Zdroj: | RSC Advances. 6:65770-65774 |
| ISSN: | 2046-2069 |
| Popis: | Biocompatible and biostable EtTP-5-loaded organic core–shell nanoparticles have been successfully evaluated for their potential as red-emitting fluorescent nanoprobes for two-photon imaging. Readily formed by Flash NanoPrecipitation, EtTP-5-based nanoprobes proved to penetrate well into multicellular spheroids and were easily imaged through several cell layers within these complex, 3D tissue models. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|