LEIOMYOMA OF THE ORAL CAVITY: A SERIES OF 8 CASES

Autor: Pablo Agustin Vargas, Ricardo Alves Mesquita, Cinthia Veronica Bardález López de Cáceres, Felipe Paiva Fonseca, Sara Ferreira Dos Santos Costa, Ruth Salomé Ferreyra De Prato, Ramiro Alejandro Tomasi
Rok vydání: 2020
Předmět:
Zdroj: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 129:e63
ISSN: 2212-4403
Popis: Leiomyomas are benign smooth muscle tumors that are uncommon in the oral cavity. The purpose of this study was to present the clinicopathologic features of a series of 8 cases of oral leiomyomas from 2 Brazilian and 1 Argentinian oral pathology service. The patients’ age at diagnosis varied from 28 to 67 years, and similar frequency in male and female patients was observed (1:1). The most commonly involved sites were lip and palate. The tumors manifested as slow-growing, asymptomatic, solitary swelling. Microscopic analysis revealed similar pattern in all cases with bundles or fascicles of spindle-shaped cells. The most common histologic subtype was angioleiomyoma. Immunohistochemical evaluation revealed positivity for smooth muscle markers. All patients underwent excision of the tumor, and no recurrence was observed. Although diagnosis is usually done on histologic analysis, immunohistochemistry is a useful tool to differentiate oral leiomyomas from other spindle cell lesions. Support: FAPEMIG.
Databáze: OpenAIRE