Study on HELLP syndrome - maternal and perinatal outcome
| Autor: | Lakshmi Narayana Kota, K. B. Gayathri, Kavitha Garikapati, Prabha Devi Kodey |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Pregnancy
medicine.medical_specialty Eclampsia HELLP syndrome business.industry Obstetrics Incidence (epidemiology) Retrospective cohort study medicine.disease Haemolysis female genital diseases and pregnancy complications Preeclampsia 03 medical and health sciences 0302 clinical medicine 030220 oncology & carcinogenesis embryonic structures medicine 030212 general & internal medicine business Complication reproductive and urinary physiology |
| Zdroj: | International Journal of Reproduction, Contraception, Obstetrics and Gynecology. 6:714 |
| ISSN: | 2320-1789 2320-1770 |
| DOI: | 10.18203/2320-1770.ijrcog20170411 |
| Popis: | Background: HELLP Syndrome is a serious obstetric complication in pregnancy characterised by haemolysis, elevated liver enzymes and low platelet count. Incidence is 0.5-0.9% of all pregnancies and in 10-20% of cases with severe preeclampsia and eclampsia. The aim of the study was to study the incidence, different clinical presentations and diagnosis of HELLP syndrome in Pre eclampsia and Eclampsia and to analyze the severity, complications, maternal and perinatal outcome.Methods: It is a 16 months period retrospective study of 102 cases of preeclampsia and eclampsia admitted in NRIMC and GH in OBGY Department with more than 28 weeks gestation. Of these, 91 cases had preeclampsia and 11 cases had eclampsia. Out of these, 15 cases developed HELLP Syndrome. The available history, clinical data, detailed laboratory investigations were studied and categorized by Mississippi classification for better analysis of complications and outcome in HELLP syndrome.Results: Of 91 cases of Preeclampsia, 12 cases (13.18%) developed HELLP syndrome and out of 11 cases of Eclampsia, 3 cases (27.27%) had HELLP Syndrome. Majority of the cases belonged to 21-25years age group and were mostly from lower Socio economic status. The present study showed 60% maternal morbidity and 6.6% maternal mortality and the perinatal morbidity and mortality was 46.6% each.Conclusions: HELLP Syndrome is a severe variant and a dreadful complication of Preeclampsia and Eclampsia, it needs early diagnosis and timely intervention in the form of termination of pregnancy to arrest further progress of pathophysiology leading to complications. |
| Databáze: | OpenAIRE |
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