Noninvasive Exploration of Nicotinic Acetylcholine Receptors In Vivo
| Autor: | A. Nordberg |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
musculoskeletal
neural and ocular physiology Central nervous system Biology Ligand (biochemistry) medicine.disease complex mixtures Nicotine Nicotinic acetylcholine receptor medicine.anatomical_structure Nicotinic agonist nervous system mental disorders medicine sense organs Alzheimer's disease Neuroscience Acetylcholine medicine.drug Acetylcholine receptor |
| Zdroj: | Handbook of Experimental Pharmacology ISBN: 9783642630279 |
| Popis: | I. In Vitro Receptor Binding Studies The discovery of the existence of nicotinic acetylcholine receptors (nAChRs) in the brain and their involvement in CNS higher functions such as learning and memory are relatively new phenomena. The nAChRs in the brain are obvious candidates for transducing cell surface interactions not only for ACh but also for several other neurotransmitters. Several studies suggest that the nAChRs may act as modulators in communicative processes in the brain. It is important to define by which mechanisms the nAChRs exert their action and find out the physiological role of the nAChRs in the CNS. It is especially important since the nAChRs seem to be involved in pathological CNS disorders where drug intervention can be implicated via interaction with the nAChRs. |
| Databáze: | OpenAIRE |
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