Sex and age differences in lipid response to chronic infection with the hepatitis C virus in the United States National Health and Nutrition Examination Surveys
| Autor: | Jeanette J. McCarthy, Xiang Qian Lao, Alexander J. Thompson, John G. McHutchison |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
education.field_of_study
medicine.medical_specialty Hepatology biology National Health and Nutrition Examination Survey business.industry Hepatitis C virus Population Blood lipids Hepatitis C Odds ratio medicine.disease_cause medicine.disease Infectious Diseases Alanine transaminase Virology Internal medicine Immunology biology.protein medicine education business Body mass index |
| Zdroj: | Journal of Viral Hepatitis. 18:571-579 |
| ISSN: | 1352-0504 |
| DOI: | 10.1111/j.1365-2893.2010.01347.x |
| Popis: | Low levels of serum lipids were reported in subjects chronically infected with the hepatitis C virus (HCV) and correlated with poorer clinical outcomes. Whether HCV 'hypo-lipidemia' is constant across age, sex and race has not been systematically explored. We therefore investigated the association between HCV infection and serum lipid levels in two independent National Health and Nutrition Examination Survey (NHANES) cohorts. HCV antibody status and serum lipid levels were obtained from 14 369 adults from NHANES 1999-2006 and 12 261 from NHANES III (enrolled in 1988-1994). In multivariable models, the prevalence of HCV-associated hypo-low density lipoprotein-cholesterol was highest among women >50 years of age in both NHANES 1999-2006 (OR: 10.51, 95% CI: 2.86, 38.62) and III (OR: 24.21, 95% CI: 6.17, 94.92), but among women |
| Databáze: | OpenAIRE |
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