Effects of Superior Cervical Ganglionectomy and Melatonin Replacement on Intra-hypothalamic LHRH Content and Pulsatile Luteinizing Hormone Release in the Mink
| Autor: | G Roch, Daniel Maurel, J-P Gautron, Monique Jallageas, N. Mas |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
photoperiodism
endocrine system medicine.medical_specialty Superior cervical ganglion Physiology medicine.medical_treatment Pulsatile flow Biology Melatonin Basal (phylogenetics) Endocrinology Physiology (medical) Internal medicine biology.animal medicine Ganglionectomy Mink Luteinizing hormone hormones hormone substitutes and hormone antagonists Ecology Evolution Behavior and Systematics medicine.drug |
| Zdroj: | Biological Rhythm Research. 28:198-215 |
| ISSN: | 1744-4179 0929-1016 |
| Popis: | Long-term effects of subcutaneous melatonin implants on intrahypothalamic LHRH content and on pulsatile luteinizing hormone release have been investigated in ganglionectomized male mink. Animals were submitted to bilateral removal of the superior cervical ganglion in mid-April. A preliminary study revealed that plasma LH concentrations remain at a basal level throughout the year following ganglionectomy. In a second experiment, one month after ganglionectomy and transfer from the natural photoperiod environment to short daylengths (LD 4:20), melatonin pellets were subcutaneously implanted to overcome deafferentation of the pineal. Progressive effects of treatment were studied 7 days, 15 days, and one, two and three months after insertion of the melatonin implants. The intra-hypothalamic LHRH content in ganglionectomized mink was at a basal level similar to that observed during seasonally sexual quiescence, or after exposure to inhibitory long days (LD 20:4). A significant and transient elevation in LHRH c... |
| Databáze: | OpenAIRE |
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