Geminal dialkylation, alkylative reduction and olefination of aliphatic aldehydes. Reaction of gem-bistriflates with higher order dialkylcyanocuprates

Autor:	J. Osío Barcina, B. Ruiz Diez, A. Garcia Martinez, L. R. Subramanian
Rok vydání:	1994
Předmět:	chemistry.chemical_compound Geminal Chemistry Yield (chemistry) Organic Chemistry Drug Discovery Organic chemistry Biochemistry Boron trifluoride
Zdroj:	Tetrahedron. 50:13231-13238
ISSN:	0040-4020
Popis:	gem -Dialkylation or alkylative reduction of α-unbranched aliphatic aldehydes 1 is advantageously achieved by reaction of the corresponding gem -bistriflates 2 with di- n -alkylcyanocuprates or di- sec - and di- tert -alkylcyanocuprates respectively. The reaction of α-branched gem -bistriflates 2 with dialkylcyanocuprates in the presence of boron trifluoride affords the olefins 6 in good yield.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c276765ea94746f353b662fbc641e16e https://doi.org/10.1016/s0040-4020(01)89331-5 Zobrazit plný text záznamu