| Autor: |
Rose Payne, Mary R. Rolfs |
| Rok vydání: |
1960 |
| Předmět: |
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| Zdroj: |
The American Journal of Medicine. 29:449-458 |
| ISSN: |
0002-9343 |
| DOI: |
10.1016/0002-9343(60)90041-3 |
| Popis: |
1.1. Leukoagglutinins were found in the serums of 147 (67 per cent) of 221 patients with febrile transfusion reactions and 12 (21 per cent) of fifty-seven patients with allergic transfusion reactions. In both types of transfusion reaction the presence of leukoagglutinins could be attributed either to prior transfusions or to pregnancies. 2.2. The proportion of women (72 per cent) with leukoagglutinin transfusion reactions was significantly larger than the proportion of men (57 per cent). 3.3. In many women leukoagglutinin transfusion reactions developed after significantly fewer transfusions than men. There were forty-four of ninety women, but none of forty-seven men, with leukoagglutinin transfusion reactions after either their first or second transfusion stimulus. 4.4. In eight of nine family studies of women in whom leukoagglutinin transfusion reactions developed after the first transfusion stimulus it was shown that the maternal serum agglutinated the leukocytes of the husband and/or the children, thus suggesting that the leukoagglutinin probably developed from stimulation by fetal leukocytes. 5.5. Leukoagglutinin transfusion reactions were consistently prevented in forty patients by the administration of blood from which the majority of leukocytes had been removed. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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