| Popis: |
In otosclerosis one deals with an osseous dystrophy of the aural capsule and in many cases with a neuropathy of the eighth nerve. Until recently the neural degenerative changes (fig. 1 A ) were not considered an essential part of the pathologic picture of progressive hereditary deafness but were regarded rather as a complication due to other factors. Surrounding the focus of otosclerotic bone is usually an area of decalcification, or halisteresis (fig. 1 B ). This area of "preparedness" finally becomes, through complete bone resorption (fig. 2 A and B ), a cavity filled with osteogenetic marrow, derived from the focus of dystrophy. In this marrow, new abnormal bone forms, thus increasing the size of the original focus. 1 A series of patients with classic otosclerosis have been treated with dietary regulation and administration of dicalcium phosphate (CaHPO 4 ), vitamins, insulin, extract of liver and other preparations and observed over a period of four years. |
