An Apparatus for Generating Aged Cigarette Smoke for Controlled Human Exposure Studies
Autor: | Sarah Nasir, Suzaynn F. Schick, D. Ken Giles, Hofer Wong, Donald Lucas, Justin Kim, John R. Balmes, Jiaxi Fang, Bryan M. Jenkins, Kathryn F. Farraro |
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Rok vydání: | 2012 |
Předmět: |
Smoke aerosol
Air exchange technology industry and agriculture complex mixtures Pollution Deposition (aerosol physics) Human exposure Environmental chemistry Environmental Chemistry Cigarette smoke Environmental science General Materials Science Particle size Cardiopulmonary disease Particle deposition |
Zdroj: | Aerosol Science and Technology. 46:1246-1255 |
ISSN: | 1521-7388 0278-6826 |
Popis: | Research has shown that cigarette smoke changes chemically and physically after it is released into indoor air, that these changes can increase secondhand smoke (SHS) toxicity, and that acute exposures to even low levels of SHS increase the risk of cardiopulmonary disease. We designed a system to reproduce realistic SHS exposures in the laboratory for use in controlled human exposure studies. We generated cigarette smoke with a smoking machine, diluted it and conducted it through a 6 m3 stainless steel flow reactor at rates equivalent to the upper ranges of normal residential air exchange rates, to create aged cigarette smoke as a model for secondhand cigarette smoke. We observed that approximately 50% of the particle mass deposited within the system and that particle deposition percentage was higher when absorbent materials were placed within the system. The particle size ranges and deposition percentages, coefficients and velocities observed for this smoke aerosol are in good agreement with published va... |
Databáze: | OpenAIRE |
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