Tonic diaphragmatic activity in critically ill children with and without ventilatory support
| Autor: | Guillaume Emeriaud, Gabrielle Constantin, Christer Sinderby, Alexandrine Larouche, Erika Massicotte, Jennifer Beck, Sandrine Essouri, Laurence Ducharme-Crevier |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Pulmonary and Respiratory Medicine
Mechanical ventilation Pediatric intensive care unit business.industry medicine.medical_treatment Diaphragmatic breathing Tonic (physiology) Interquartile range Anesthesia Pediatrics Perinatology and Child Health Medicine Lung volumes Expiration business Positive end-expiratory pressure |
| Zdroj: | Pediatric Pulmonology. 50:1304-1312 |
| ISSN: | 8755-6863 |
| Popis: | SummaryBackground Infants have to actively maintain their end expiratory lung volume (EELV). In mechanically ventilated infants, the diaphragm stays activated until the end of expiration (tonic activity), contributing to EELV maintenance. It is unclear whether tonic activity compensates for the lack of laryngeal braking due to intubation or if it is normally present. Objective To determine if tonic diaphragm activity remains after extubation in infants, and if it can be observed in older children. Methods Prospective observational study of pediatric patients ventilated for >24 hr. Diaphragm electrical activity (EAdi) was recorded using a specific nasogastric catheter during four periods: (i) the acute phase, (ii) pre-extubation, (iii) post-extubation, and (iv) at PICU discharge. Tonic EAdi was defined as the EAdi in the last quartile of expiration. Results Fifty-five patients, median age 10 months (Interquartile range: 1–48) were studied. In infants ( |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text