An overview of Immunopathogenesis towards COVID-19 infection
Autor: | Noha Saber Shafik, Mona Mohammed Abd El Rhman |
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Rok vydání: | 2020 |
Předmět: |
biology
Coronavirus disease 2019 (COVID-19) business.industry viruses 010102 general mathematics Disease biochemical phenomena metabolism and nutrition Major histocompatibility complex medicine.disease 01 natural sciences World health Virus respiratory tract diseases 03 medical and health sciences Pneumonia 0302 clinical medicine Immune system Immunology biology.protein medicine 030212 general & internal medicine 0101 mathematics business Virus classification |
Zdroj: | Sohag Medical Journal. 24:69-75 |
ISSN: | 1687-8353 |
Popis: | Patients complaining from cough, fever, dyspnea, and severe pneumonia were recorded in Wuhan, China in late December 2019 due to an unkown microbial agent. Virus genome sequencing of the examined patients during this period confirmed the presence of β- CoV strain. This extracted new β-CoV exhibits 88 percent similarity to the series of 2 severe bat-derived acute respiratory syndromes (SARS)-like corona viruses, bat-SL-CoVZC45 and bat-SL-CoVZXC21, and about 50 percent identical to the MERS-CoV series. Later, the International Commission for Virus Classification called the novel β-CoV "SARS-CoV-2." On the eleventh of February 2020, the World Health Organization (WHO) reported another name for the disease caused by the 2019-n CoV: which is Corona Virus Disease (COVID-19). Several complex immune system mechanisms exist against the newly discovered COVID-19. Communication has undergone between different branches of the immune system, but the exact mechanism remained unclear until now. This study helps to clarify COVID-19 molecular immune pathogenesis. |
Databáze: | OpenAIRE |
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