The Role of Histone Modifications in the Pathogenesis of Diabetic Kidney Disease

Autor:	Christodoula Kourtidou, Konstantinos Tziomalos
Rok vydání:	2023
Předmět:	Inorganic Chemistry Organic Chemistry General Medicine Physical and Theoretical Chemistry Molecular Biology Spectroscopy Catalysis Computer Science Applications
Zdroj:	International Journal of Molecular Sciences. 24:6007
ISSN:	1422-0067
DOI:	10.3390/ijms24066007
Popis:	Diabetic kidney disease (DKD) is the leading cause of chronic kidney disease. The pathogenesis of DKD is multifactorial, with several molecular pathways implicated. Recent data suggest that histone modification plays an important role in the development and progression of DKD. Histone modification appears to induce oxidative stress, inflammation and fibrosis in the diabetic kidney. In the present review, we summarize the current knowledge on the association between histone modification and DKD.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c22ed204f3fd5b6624c5cb676ef77a4a https://doi.org/10.3390/ijms24066007 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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