Two cases of atypical meningioma with pulmonary metastases: A comparative cytogenetic analysis of chromosomes 1p and 22 and a review of the literature
| Autor: | Wolf Mueller, Helene Hantmann, Tanja Gradistanac, Heidrun Holland, J. Meixensberger, Clara Frydrychowicz, Karl Titus Hoffmann, Wolfgang Krupp |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
Pathology Lung business.industry Atypical meningioma Cytogenetics General Medicine Who grade medicine.disease nervous system diseases Pathology and Forensic Medicine Tumor recurrence Metastasis Meningioma medicine.anatomical_structure otorhinolaryngologic diseases Medicine In patient Neurology (clinical) business |
| Zdroj: | Neuropathology. 35:175-183 |
| ISSN: | 0919-6544 |
| Popis: | We present two cases of atypical meningioma WHO grade II with a history of multiple local recurrences and late pulmonary metastases. Comparative cytogenetic analyses on 1p and 22q confirmed clonal origin of the primary intracranial meningiomas and the pulmonary metastases in both cases. These cases illustrate the importance of close neuroradiological follow-up to detect tumor recurrence in patients with atypical meningiomas WHO grade II even with clinically stable disease and should sensitize clinicians to late extracranial metastases of these tumors, especially to the lung. In an effort to elucidate common clinical features of metastatic meningiomas, especially to the lung, the literature was reviewed from 1995 to 2014, identifying a total of 45 published cases. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text