Detection of Intrathoracic Infectious Lesions Using 111In-Diethylenetriamine Pentaacetic Bicyclic Anhydride-IgG (111In-DTPA-IgG) Scintigraphy

Autor: Hiroo Wada, Mari Iguchi, Hajime Goto, Kazumi Yuasa, Ryuji Ieki, Tatsuru Okamura, Tomohiro Ota, Kenzo Suzuki
Rok vydání: 1998
Předmět:
Zdroj: Journal of the Japanese Association for Infectious Diseases. 72:128-135
ISSN: 1884-569X
0387-5911
Popis: The utility of 111In-DTPA-IgG imaging for the detection of intrathoracic lesions was evaluated in 10 patients with the suspicion of inflammatory or infectious diseases. They were intravenously administered 40 or 80 MBq of 111In-DTPA-IgG, and scanned after 24 or 48 hours. Of these, 8 cases, consisted of 4 cases with pneumonia and 2 cases with lung abscess and one case of pulmonary tuberculosis and one of a tuberculous pleuritis, showed true positive results. Others were one false negative case of pneumonia and one true negative case of lung cancer. Overall sensitivity and specificity were 88.9% and 100%, respectively. There were no cases which showed side effects or abnormal laboratory findings caused by the radiopharmaceuticals administered. Thus, 111In-DTPA-IgG imaging is a useful tool for the detection of intrathoracic infectious lesions.
Databáze: OpenAIRE