Stereoselective Total Synthesis of (-)-Isocladospolide B and Cladospolide B and C

Autor:	S. S. Mandal, J. S. Yadav
Rok vydání:	2011
Předmět:	Cladospolide B chemistry.chemical_classification Chemistry Stereochemistry Jacobsen epoxidation Organic Chemistry Enantioselective synthesis Total synthesis Stereoselectivity Lactone Stereocenter Kinetic resolution
Zdroj:	Synlett. 2011:2803-2806
ISSN:	1437-2096 0936-5214
DOI:	10.1055/s-0031-1289868
Popis:	The enantioselective synthesis of bioactive butenolides isocladospolide B, cladospolide B, and cladospolide-C has been achieved from (S)-propylene oxide. Of the three stereogenic centers, the C-4/C-5 vic-diol was obtained using diastereo- and enantioselective Brown hydroxycrotylation, while the C-11 stereocenter was created by Jacobsen hydrolytic kinetic resolution.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c1fd979ee5ec2da741aafa08494daaef https://doi.org/10.1055/s-0031-1289868 Zobrazit plný text záznamu