Chemical Composition of the Essential Oil from the Fresh Fruits of Xylopia Laevigata and its Cytotoxic Evaluation
| Autor: | Thanany Brasil da Silva, Emmanoel V. Costa, Daniel P. Bezerra, Cinara Oliveira D´Sousa Costa, Milena Botelho Pereira Soares |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Pharmacology
Limonene Chromatography biology 010405 organic chemistry Chemistry Plant Science General Medicine Mass spectrometry biology.organism_classification 01 natural sciences 0104 chemical sciences law.invention 010404 medicinal & biomolecular chemistry chemistry.chemical_compound Complementary and alternative medicine law Drug Discovery Botany Cytotoxic T cell Flame ionization detector Gas chromatography Chemical composition Essential oil Xylopia |
| Zdroj: | Natural Product Communications. 11:1934578X1601100 |
| ISSN: | 1555-9475 1934-578X |
| Popis: | The essential oil obtained by hydrodistillation from the fresh fruits of Xylopia laevigata was analyzed by gas chromatography using a flame ionization detector (GC–FID) coupled to a mass spectrometer (GC–MS). Monoterpenes predominated, forming 95.0% of the total essential oil. The major constituents identified were limonene (56.2%), α-pinene (28.0%), and β-pinene (5.5%). Cytotoxic activity against tumor cell lines and non-tumor cells was also investigated; however, neither the essential oil nor its major constituents evaluated presented any cytotoxic activity (IC50 > 25.0 μg mL−1). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|