Quantitative estimation of benzylisoquinoline derivatives by coulometric titration

Autor:	S. G. Abdullina, A. I. Samigullin, G. K. Budnikov, Guzel Ziyatdinova
Rok vydání:	2008
Předmět:	Pharmacology End point Chromatography Relative standard deviation DROTAVERINE HCL chemistry.chemical_element Coulometry Papaverine hcl chemistry.chemical_compound chemistry Drug Discovery Chlorine medicine Drotaverine Benzylisoquinoline medicine.drug
Zdroj:	Pharmaceutical Chemistry Journal. 42:98-101
ISSN:	1573-9031 0091-150X
DOI:	10.1007/s11094-008-0068-z
Popis:	A method for estimating papaverine HCl and drotaverine HCl by coulometric titration with biamperometric indication of the end point was developed. The stoichiometric coefficients of the reactions of papaverine and drotaverine with electrogenerated chlorine were determined. Microgram quantities of agents in substance and therapeutic forms were estimated with a relative standard deviation (RSD) of 0.01–0.03.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c1cda99ef0c39bfa5b3b82bd024a540e https://doi.org/10.1007/s11094-008-0068-z Zobrazit plný text záznamu Plný text ve formátu PDF