GRANULAR CELL TUMOR MIMICKING AN EOSINOPHILIC ULCER ON THE TONGUE
| Autor: | Pablo Agustin Vargas, Márcio Ajudarte Lopes, Lorena Passoni Vervloet, Alan Roger Santos-Silva, Patrícia Maria Fernandes, Gleyson Kleber do Amaral-Silva, Diego Tetzner Fernandes |
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| Rok vydání: | 2020 |
| Předmět: |
Granular cell tumor
Pathology medicine.medical_specialty medicine.diagnostic_test business.industry Connective tissue Soft tissue Nodule (medicine) medicine.disease Pathology and Forensic Medicine Lesion medicine.anatomical_structure Tongue Biopsy Eosinophilic medicine Radiology Nuclear Medicine and imaging Dentistry (miscellaneous) Surgery Oral Surgery medicine.symptom business |
| Zdroj: | Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 129:e84-e85 |
| ISSN: | 2212-4403 |
| DOI: | 10.1016/j.oooo.2019.06.346 |
| Popis: | Granular cell tumor (GCT) is an uncommon benign neoplasia of soft tissue that possibly arises from neural cells, especially Schwann cells. In the oral cavity, the most frequent site is the tongue. Usually, the clinical appearance is a solitary submucosal nodule, painless and nonulcerated, located in the dorsum of the tongue. Women have twice more predilection than men, and mean age ranges from fourth to sixth decades. This case report consists in a 56-year-old man referred for evaluation of a 6-month evolution of an ulcerated lesion in the right lateral border of tongue. Clinically, a discoid ulceration with elevated erythematous center and whiteness halo was observed. The clinical hypothesis was an eosinophilic ulcer. After excisional biopsy and histologic processes, a predominant group of eosinophilic cells with granular cytoplasm raised from connective tissue to ulcerated surface could be visualized. S100 immunohistochemical reaction was made, and a strong staining of these cells confirmed the final diagnosis of GCT. |
| Databáze: | OpenAIRE |
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