Diffusion- and T2-weighted MR Imaging of the Liver: Effect of Intravenous Administration of Gadoxetic Acid Disodium
| Autor: | Katsuhiro Sano, Tomoaki Ichikawa, Tsutomu Araki, Utaroh Motosugi, Hironobu Sou, Ali Muhi |
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| Rok vydání: | 2012 |
| Předmět: | |
| Zdroj: | Magnetic Resonance in Medical Sciences. 11:185-191 |
| ISSN: | 1880-2206 1347-3182 |
| Popis: | PURPOSE We evaluated the effect of intravenous administration of gadoxetic acid disodium to hepatic lesions and liver parenchyma on T₂-weighted (T₂WI) and diffusion-weighted imaging (DWI). MATERIALS AND METHODS One hundred and one consecutive patients with 259 hepatic lesions underwent T₂WI and DWI (b-values of 500 and 1000 s/mm²) before and after gadoxetic acid administration. We compared the ratio of signal intensity (SIR) of the liver parenchyma and hepatic lesions, the ratio of contrast intensity of the lesion to the liver (CIR), the apparent diffusion coefficients (ADCs) of the liver and lesions, and lesion detectability between pre- and post-contrast images. RESULTS SIRs, CIRs, and ADC of focal hepatic lesions were comparable on pre- and post-contrast images, and lesion detectability did not differ significantly between pre- and post-contrast T₂WI and DWI. The SIRs of the liver parenchyma were significantly lower on post-contrast DWI (1.4±0.68 [b=500 s/mm²] and 1.71±0.67 [b=1000 s/mm²]) than pre-contrast images (1.89±0.68 [b=500 s/mm²] and 2.26±0.78 [b=1000 s/mm²]) (P |
| Databáze: | OpenAIRE |
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