LiBr as an Efficient Catalyst for One-pot Synthesis of Hantzsch 1,4-Dihydropyridines under Mild Conditions

Autor:	Rajesh Patel, Lal Dhar S. Yadav, Geeta Watal, Vishnu P. Srivastava, Deepak Yadav
Rok vydání:	2011
Předmět:	chemistry.chemical_classification Lithium bromide One-pot synthesis chemistry.chemical_element General Chemistry Condensation reaction Aldehyde chemistry.chemical_compound chemistry Organic chemistry Lithium Acetonitrile Efficient catalyst Ammonium acetate
Zdroj:	Chinese Journal of Chemistry. 29:118-122
ISSN:	1001-604X
Popis:	A simple, inexpensive and efficient one-pot synthesis of 1,4-dihydropyridines has been accomplished via lithium bromide-catalyzed Hantzsch three-component condensation reaction of an aldehyde, α,β-ketoester and ammonium acetate in acetonitrile at room temperature in good to excellent yields. The present protocol is applicable to wide range of substrates including aliphatic, aromatic and heterocyclic aldehydes affording 1,4-dihydropyridines.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c19c3c78b54e25b33d8a7694312d23e6 https://doi.org/10.1002/cjoc.201190036 Zobrazit plný text záznamu Plný text