Antibacterial activity and mode of action of plant flavonoids against Proteus vulgaris and Staphylococcus aureus
| Autor: | Shinkichi Tawata, Nobuyasu Enoki, Chikao Nishino, Akihisa Mori |
|---|---|
| Rok vydání: | 1987 |
| Předmět: |
chemistry.chemical_classification
biology medicine.drug_class fungi Flavonoid Antibiotics Proteus vulgaris food and beverages Plant Science General Medicine Horticulture medicine.disease_cause biology.organism_classification Biochemistry Enterobacteriaceae Microbiology chemistry Staphylococcus aureus medicine heterocyclic compounds Mode of action Antibacterial activity Molecular Biology Bacteria |
| Zdroj: | Phytochemistry. 26:2231-2234 |
| ISSN: | 0031-9422 |
| DOI: | 10.1016/s0031-9422(00)84689-0 |
| Popis: | (−)-Epigallocatechin, an antibiotic found in Elaeagnus glabra, and 28 other related plant flavonoids were tested for their antibacterial activity against Proteus vulgaris and Staphylococcus aureus. A free 3′,4′,5′-trihydroxy B-ring and a free 3-OH were necessary for antibacterial activity. DNA synthesis was predominantly inhibited by the active flavonoids in P. vulgaris, whereas RNA synthesis was inhibited in S. aureus. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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