MO235EFFECT OF OMEGA-3 POLYUNSATURATED FATTY ACID SUPPLEMENTATION ON GLYSEMIC CONTROL AND RENAL FUNCTION IN TYPE 2 DIABETIC PATIENTS WITH CHRONIC KIDNEY DISEASE
| Autor: | Canan Ersoy, Mehmet Usta, Yavuz Ayar, Alpaslan Ersoy, İsminur Saka Karagoz, Gultekin Goksel |
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| Rok vydání: | 2021 |
| Předmět: |
chemistry.chemical_classification
Transplantation Fasting lipid profile medicine.medical_specialty business.industry Renal function medicine.disease Endocrinology Polyunsaturated fatty acid supplementation chemistry Nephrology Diabetes mellitus Internal medicine Medicine business Kidney disease Polyunsaturated fatty acid |
| Zdroj: | Nephrology Dialysis Transplantation. 36 |
| ISSN: | 1460-2385 0931-0509 |
| DOI: | 10.1093/ndt/gfab092.00113 |
| Popis: | Background and Aims The aim of this study was to evaluate the short-term effects of omega-3 polyunsaturated fatty acids (n-3 PUFA) supplementation on glycemic control and renal function in type 2 diabetic patients with chronic kidney disease. Method Twenty-five diabetic patients received medication containing 2 g/day n-3 PUFA orally in addition to standard treatments. Their estimated glomerular filtration rates (eGFR) were Results After three months of supplementation, the changes in serum creatinine, uric acid, eGFR and urinary albumin excretion levels did not reach statistical significance. There was no difference between serum glucose, HbA1C and lipid profile values before and after the n-3 PUFA supplementation in patients. Only serum albumin significantly increased from 4.10±0.26 to 4.28±0.31 g/dL (p=0.016), and systolic blood pressure decreased from 121.4±14.5 to 116.6±14.9 mmHg (p=0.001). Conclusion Short-term n-3 PUFA supplementation did not affect renal function and glycemic control in patients with type 2 diabetes with chronic kidney disease. |
| Databáze: | OpenAIRE |
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