Novel stilbenes isolated from the root bark of Ekebergia benguelensis

Autor: T E Chagwedera, A. Douglas Kinghorn, Heebyung Chai, Daniel Chávez, Qi Gao, Geoffrey A. Cordell, Norman R. Farnsworth, John M. Pezzuto
Rok vydání: 2001
Předmět:
Zdroj: Tetrahedron Letters. 42:3685-3688
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(01)00560-3
Popis: Four novel stilbenes ( 1 – 4 ) were isolated from the root bark of Ekebergia benguelensis . The structures were established by spectroscopic methods including 2D NMR analysis. The structure of 1 , a new stilbene–coumarin hybrid representing a novel skeleton, was confirmed by single X-ray analysis. Compounds 1 – 4 were evaluated against a panel of human cancer cell lines.
Databáze: OpenAIRE