Clinical Approach to Type 3 von Willebrand Disease
| Autor: | Dominder Kaur, Sarah H. O'Brien |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
congenital
hereditary and neonatal diseases and abnormalities medicine.medical_specialty Antifibrinolytic biology Factor replacement Internal bleeding business.industry medicine.drug_class medicine.disease Gastroenterology Vw Antigen Von Willebrand factor hemic and lymphatic diseases Antifibrinolytic agent Internal medicine biology.protein medicine Von Willebrand disease medicine.symptom Desmopressin business circulatory and respiratory physiology medicine.drug |
| Zdroj: | Pediatric Bleeding Disorders ISBN: 9783030316600 |
| Popis: | Type 3 von Willebrand disease (VWD) is a severe quantitative deficiency of von Willebrand factor (VWF) that results in negligible circulating factor levels. As VWF is the carrier protein for factor VIII (FVIII), there is an accompanying FVIII deficiency. Patients with type 3 VWD experience more frequent bleeding symptoms than other VW types. Spontaneous internal bleeding, like joint and muscle bleeding, can also occur. Diagnosis is made by quantifying VW antigen and activity levels, which are typically |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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