Detection of vitellogenin, an endocrine disrupter biomarker, using AlGaN/GaN high electron mobility transistors

Autor:	Byung Hwan Chu, Andrew M. Wowchak, P. Rajagopal, Yu-Lin Wang, Stephen J. Pearton, Fan Ren, Edwin L. Piner, B. Cui, Amir M. Dabiran, Peter Chow, Jerry W. Johnson, Jenshan Lin, Chih-Yang Chang, K. J. Linthicum, John C. Roberts, Nancy D. Denslow, Kevin J. Kroll
Rok vydání:	2011
Předmět:	food.ingredient Chromatography biology Transistor Analytical chemistry Algan gan High-electron-mobility transistor Condensed Matter Physics Serum samples law.invention chemistry.chemical_compound Vitellogenin Bass (fish) food chemistry law biology.protein Thioglycolic acid High electron
Zdroj:	physica status solidi c. 8:2486-2488
ISSN:	1610-1642 1862-6351
Popis:	Real time detection of vitellogenin in largemouth bass serum was demonstrated using AlGaN/GaN HEMTs. Anti-vitellogenin antibodies were chemically anchored to the gold-coated gate area of the HEMT by thioglycolic acid. The potential difference that occurred from the vitellogenin antigen/antibody interaction induced a drain current change. The sensor was able to detect as low as 4 µg/mL Vtg. Successful detection in serum samples shows that HEMTs have the potential to be used as biological sensors in real-world applications (© 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim)
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c16e4f3d5cc88f53dace6e285efa5f7d https://doi.org/10.1002/pssc.201001171 Zobrazit plný text záznamu Plný text