Autor:	Laura E. Blue
Rok vydání:	2022
Předmět:	Analytical Chemistry
Zdroj:	LCGC North America. :360-362
ISSN:	1939-1889 1527-5949
DOI:	10.56530/lcgc.na.yy3879t6
Popis:	Most molecules with therapeutic value have at least one chiral center, requiring resolution of both achiral and chiral impurities. Separate achiral and chiral methods are the most used methodologies, but two-dimensional (2D) methods and columns in series have also been implemented. Having a mixed-mode column that can provide both achiral and chiral resolution in one-dimension (1D) would significantly improve impurity profile understanding and reduce testing workload.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c16b397126e625bb736e6f262a9e37b7 https://doi.org/10.56530/lcgc.na.yy3879t6 Zobrazit plný text záznamu