Preparation of Derivatives of 2-Cyano-3-(5-N-arylamino- or 5-N-Alkyl-N-phenylamino-2-furyl)propenoic Acids

Autor:	František Považanec, Pavel Čepec, Peter Šafář, N. Pronayova
Rok vydání:	1997
Předmět:	chemistry.chemical_classification Hydrolysis chemistry.chemical_compound chemistry General Chemistry Malonic acid Medicinal chemistry Alkyl
Zdroj:	Collection of Czechoslovak Chemical Communications. 62:1105-1113
ISSN:	1212-6950 0010-0765
Popis:	(5-Bromo-2-furyl)methylidenemalonodinitrile (1) reacted with substituted aromatic amines under formation of (5-N-arylamino-2-furyl)methylidenemalonodinitriles 2a-2h whereas no reaction was observed with N-alkyl-N-phenylamines. Derivatives of 2-cyano-3-(5-N-alkyl-N-phenylamino-2-furyl)- propenoic acid 5a-5o were prepared by reaction of the corresponding N-alkylanilines with 5-bromo-2-furancarbaldehyde, followed by hydrolysis of the obtained Eiji salts and reaction with malonic acid derivatives.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c15e940143b2390c6d3f3b6dbfb9eece https://doi.org/10.1135/cccc19971105 Zobrazit plný text záznamu