| Popis: |
Uterine fibroids is the most common tumour of the reproductive system. Despite the presence of a large number of ongoing studies, the study of this pathology is still relevant due to many unresolved pathogenesis issues. The pres-ence of genetic predisposition, belonging to the black race, age, especially late reproductive, early menarche, absence of births in the history and, of course, obesity are considered as risk factors for uterine fibroids development. In this re-gard, the study aimed to study the relationship between fetal macrosomia, obesity and the risk of the formation of hor-mone-dependent tumours of the genitals. The research methods included the study of apoptosis processes in simple and proliferating uterine fibroids by determining the level of the ligand inducing apoptosis, which made it possible to iden-tify a group of patients with a high proliferative activity of myomatous nodes, and when analyzing the patient histories, the most significant signs and characteristics were identified, in the presence of which significantly increases the likeli-hood of detecting uterine fibroids. The results of the study presented in this paper allow us to set the necessary accents and form risk groups for uterine fibroids development and, above all, the most mitotically active variant - proliferating uterine fibroids. Key words: simple uterine fibroids, proliferating uterine fibroids, risk factors, pelvic ultrasound, macrosomia, obesity. |
