Primary amenorrhea due to juvenile granulosa-cell tumor of the ovary: A case report
| Autor: | Setsuko Nakayama, Tomoko Adachi, Shoko Shimizu, Masao Nakabayashi, Hideki Sato, Hideo Matsui |
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| Rok vydání: | 2012 |
| Předmět: |
endocrine system
medicine.medical_specialty endocrine system diseases business.industry Thyroid Obstetrics and Gynecology Gonadal dysgenesis Ovary medicine.disease Follicle-stimulating hormone Endocrinology medicine.anatomical_structure Hypothalamus Internal medicine medicine Menarche Juvenile business hormones hormone substitutes and hormone antagonists Hormone |
| Zdroj: | Journal of Obstetrics and Gynaecology Research. 38:597-600 |
| ISSN: | 1341-8076 |
| Popis: | In general, primary amenorrhea is caused by gonadal dysgenesis, anomalies of internal or external genitalia with or without chromosomal anomalies, and sometimes by hormonal abnormalities that affect the hypothalamus, pituitary, ovaries, adrenals or thyroid, or by chronic or metabolic diseases. We report a rare case of a juvenile granulosa-cell tumor of the ovary that caused primary amenorrhea in a 16-year-old girl. Her hormonal profiles before the operation were characterized by an extremely low level of follicle-stimulating hormone (FSH), a relatively low level of estradiol and a high level of inhibin B. The patient had menarche after the removal of the tumor. Her elevated serum FSH after the operation was the result of a decreased serum level of inhibin that had been produced by the tumor. The present case highlights that a granulosa-cell tumor, known as an inhibin-secreting tumor, should be considered when treating primary amenorrheic girls. |
| Databáze: | OpenAIRE |
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