Synthesis of Chiral Melatonin Salts of Dithiophosphoric Acids Using Monoterpenyl Alcohol

Autor: Ilnar D. Nizamov, Ramazan Z. Salikhov, Elvira S. Batyeva, G. G. Sergeenko, Il'yas S. Nizamov, R. A. Cherkasov, Oscar K. Pozdeev, Yevgeniy N. Nikitin, R. R. Davletshin, Marina P. Shulaeva
Rok vydání: 2020
Předmět:
Zdroj: Asian Journal of Chemistry. 32:1511-1514
ISSN: 0975-427X
0970-7077
DOI: 10.14233/ajchem.2020.22509
Popis: Dithiophosphoric acids in the terms of (S)-(–)-menthol, (1S)-endo-(–)-borneol,(1R)-endo-(+)-fenchyl alcohol and (1S,2S,3S,5R)-(+)-isopinocampheol react with melatonin to form chiral N-acetyl 5-methoxytryptammonium dithiophosphates. The interations proceed via increase in the coordination of indole nitrogen of melatonin. The antibacterial and antifungal activity of N-acetyl 5-methoxytryptammonium dithiophosphate containing (+)-fenchyl substituent was established
Databáze: OpenAIRE