Group 2 Pulmonary Hypertension
| Autor: | Evelyn M. Horn, Craig B. Clark |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
business.industry General Medicine Disease 030204 cardiovascular system & hematology medicine.disease Pulmonary hypertension Pathophysiology 03 medical and health sciences 0302 clinical medicine Internal medicine medicine.artery Epidemiology Pulmonary artery medicine Cardiology Pulmonary venous hypertension 030212 general & internal medicine Left heart disease Cardiology and Cardiovascular Medicine business Pulmonary wedge pressure |
| Zdroj: | Cardiology Clinics. 34:401-411 |
| ISSN: | 0733-8651 |
| DOI: | 10.1016/j.ccl.2016.04.010 |
| Popis: | Pulmonary hypertension from left heart disease (PH-LHD) is the most common form of PH, defined as mean pulmonary artery pressure ≥25 mm Hg and pulmonary artery wedge pressure ≥15 mm Hg. PH-LHD development is associated with more severe left-sided disease and its presence portends a poor prognosis, particularly once right ventricular failure develops. Treatment remains focused on the underlying LHD and despite initial enthusiasm for PH-specific therapies, most studies have been disappointing and their routine clinical use cannot be recommended. More work is urgently needed to better understand the pathophysiology underlying this disease and to develop effective therapeutic strategies. |
| Databáze: | OpenAIRE |
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