1H,3H and13C NMR studies on porphobilinogen

Autor:	N. E. Mackenzie, Paul E. Fagerness, A. I. Scott, J. N. S. Evans
Rok vydání:	1985
Předmět:	biology Porphobilinogen synthase Stereochemistry General Chemistry Nuclear magnetic resonance spectroscopy Carbon-13 NMR Porphyrin chemistry.chemical_compound Biosynthesis chemistry In vivo Porphobilinogen biology.protein Organic chemistry General Materials Science Pyrrole
Zdroj:	Magnetic Resonance in Chemistry. 23:939-944
ISSN:	1097-458X 0749-1581
DOI:	10.1002/mrc.1260231112
Popis:	A key intermediate in porphyrin and corrin biosynthesis is the trisubstituted pyrrole porphobilinogen (PBG). The fate of PBG in the biosynthesis of porphyrins and corrins has been monitored by NMR spectroscopy in vivo and in vitro employing various nuclei. The syntheses of highly tritiated PBG and its immediate precursor 5-aminolevulinic acid (ALA) are reported, together with 3H, 1H and 13C assignments.
Databáze:	OpenAIRE
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