Selective detection of pyrophosphate by new tripodal amine calix[4]arene-based Cu(II) complexes using indicator displacement strategy

Autor:	Chomchai Suksai, Chaveng Pakawatchai, Wittaya Ngeontae, Sarayut Watchasit, Arpadsara Kaowliew, Thawatchai Tuntulani
Rok vydání:	2010
Předmět:	Steric effects HEPES Stereochemistry Organic Chemistry Pyrocatechol violet Biochemistry Medicinal chemistry Pyrophosphate chemistry.chemical_compound Cone conformation chemistry Drug Discovery Amine gas treating Selectivity
Zdroj:	Tetrahedron Letters. 51:3398-3402
ISSN:	0040-4039
Popis:	Mono- and dinuclear Cu(II) complexes of p-tert-butylcalix[4]arene (CuL1 and CuL2, respectively) were synthesized, and their anion recognition abilities were explored. Recognition is efficiently signaled through the displacement of pyrocatechol violet bound to the receptor. For CuL2, recognition selectivity is ascribed to the tuning of the distance between donor atoms of anion guests and their ability to encompass the Cu2+–Cu2+ distance within the cleft of CuL2. In addition, the preorganization of calix[4]arene in the cone conformation and steric hindrance of two bulky tripodal amine moieties are important factors in controlling the Cu2+–Cu2+ distance. These factors caused CuL2 to recognize pyrophosphate selectively with respect to other inorganic anions in 80/20 (v/v%) MeCN/H2O solution buffered with 10 mM HEPES at pH 6.4.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c0f762eb764bde475226e230c99f3581 https://doi.org/10.1016/j.tetlet.2010.04.095 Zobrazit plný text záznamu Full Text from ScienceDirect