Sleep deprivation in depression
| Autor: | Alexander Kharraz, Ulrich Frick, J M Aigner, Berthold Langguth, Rainer Wiegand, Peter Eichhammer, Goeran Hajak |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
business.industry
musculoskeletal neural and ocular physiology medicine.medical_treatment Stimulation General Medicine General Biochemistry Genetics and Molecular Biology law.invention Transcranial magnetic stimulation Sleep deprivation nervous system Randomized controlled trial law Anesthesia mental disorders Severity of illness Medicine Antidepressant General Pharmacology Toxicology and Pharmaceutics medicine.symptom business psychological phenomena and processes Depression (differential diagnoses) Morning |
| Zdroj: | Life Sciences. 70:1741-1749 |
| ISSN: | 0024-3205 |
| DOI: | 10.1016/s0024-3205(02)01479-0 |
| Popis: | Partial sleep deprivation (PSD) has a profound and rapid effect on depressed mood. However, the transient antidepressant effect of PSD - most patients relapse after one night of recovery sleep—is limiting the clinical use of this method. Using a controlled, balanced parallel design we studied, whether repetitive transcranial magnetic stimulation (rTMS) applied in the morning after PSD is able to prevent this relapse. 20 PSD responders were randomly assigned to receive either active or sham stimulation during the following 4 days after PSD. Active stimulation prolonged significantly (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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