Granulomatous inflammation in lymph nodes draining cancer: significant association or just coincidence- Diagnostic dilemma

Autor:	Hemant R. Kokandakar, Rakesh Kumar J. Ajmera, Rohini Shewale
Rok vydání:	2020
Předmět:	Pathology medicine.medical_specialty business.industry medicine.medical_treatment Cancer medicine.disease Malignancy Metastasis Radiation therapy hemic and lymphatic diseases Granuloma Medicine Lymph Sarcoidosis business Foreign body granuloma
Zdroj:	IP Journal of Diagnostic Pathology and Oncology. 3:295-298
ISSN:	2581-3706 2581-3714
Popis:	Causes of granulomatous inflammation are broadly divided into infective and non infective. Infective causes Includes myocbacterial, fungal or parasitic origin. Non infective includes: Foreign body granuloma, sarcoidosis, crohn’s disease. Granuloma formation seen in cancer patients may be due to previous chemotherapy or radiation therapy. However in many cases mechanism in granuloma formation and its therapeutic outcome in cancer patients remains unknown. Careful scrutiny in all cases is required where coexisting malignancy was suspected along with granuloma formation in lymph nodes draining cancers. Exact cause of granuloma formation in lymph nodes draining cancer remains unknown however immunological reaction to tumour antigens is proposed theory .These granuloma may represent impending metastasis or already existing metastasis in patients who received neoadjuvant chemoradiation. Keywords: Granuloma, Lymph nodes, Metastasis, Chemoradiation.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c0e7ee2bf86b1876fda101390bb67e1b https://doi.org/10.18231/2581-3706.2018.0060 Zobrazit plný text záznamu