Prospective assessment of INTERGROWTH-21st and World Health Organization estimated fetal weight reference curves
| Autor: | Yvonne Kwun Yue Cheng, Jing Lu, Yiu Man Chan, Daljit Singh Sahota, Tak Yeung Leung |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
Fetus education.field_of_study 030219 obstetrics & reproductive medicine Radiological and Ultrasound Technology Obstetrics business.industry Singleton Birth weight Population Obstetrics and Gynecology Gestational age General Medicine 03 medical and health sciences 0302 clinical medicine Reproductive Medicine Interquartile range medicine Gestation Radiology Nuclear Medicine and imaging 030212 general & internal medicine business education Cohort study |
| Zdroj: | Ultrasound in Obstetrics & Gynecology. 51:792-798 |
| ISSN: | 0960-7692 |
| DOI: | 10.1002/uog.17514 |
| Popis: | Objectives To assess the suitability of the new INTERGROWTH-21 and WHO estimated fetal weight (EFW) references. Methods This was a prospective cross-sectional cohort study. Viable singleton pregnancies at 11-13 weeks were randomized to undergo a standardized fetal biometric scan after 20 weeks. EFW were predicted using both the Hadlock and INTERGROWTH-21 weight estimation models formulaes. Population specific EFW gestation references were constructed. Z-scores were used to compare the population specific reference against the two international size references, INTERGROWTH-21 and WHO. Gestation Adjusted Projection (GAP) was used to assess the difference predicted EFW on day of delivery and birthweight for fetuses having biometry scans ≥ 34 weeks. Results Fetuses of 970 participants had biometry scans. The median (Interquartile range (IQR)) number of scans per gestational week was 48 (43-53). Z-score comparison indicated that WHO 10th, 50th and 90th centiles of the EFW reference were consistently higher than the corresponding local centiles whilst INTERGROWTH-21 10th centile was lower. Less than 2%, of fetuses scanned on or after 34 weeks would be considered as potentially large for gestational age irrespective of which model was used to predict weight. Adopting the WHO international reference would result in approximately 1 in 6 fetuses being regarded as potentially small for gestation, a 50 percent increase over that determined using a population specific reference. Systematic error of extrapolated EFW were similar, ranging from 5.5% to 7.4%. Conclusions Centers seeking to use new references such as the INTERGROWTH-21 and or WHO international references as a means of determining whether a fetus is small or large for gestation would be advised to assess the suitability of these references within their own population using standardized methodology. |
| Databáze: | OpenAIRE |
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