A report on a prospective trial of no initial therapy in patients with asymptomatic favourable prognosis non-Hodgkin's lymphoma

Autor: C. J. Williams, F. R. Macbeth, J. M. A. Whitehouse, R. D. H. Ryall, Graham M. Mead
Rok vydání: 1984
Předmět:
Zdroj: Hematological Oncology. 2:179-188
ISSN: 0278-0232
Popis: Thirty-one (58 per cent) of a group of fifty-three unselected patients with stage II-IV favourable prognosis non-Hodgkin's lymphoma were regarded as being eligible for a prospective study of no initial therapy. Seventeen of these patients (55 per cent) have required no treatment for periods from 6 + -47 + months, (median 18 months) and fourteen patients have been treated with chemotherapy for progressive disease after a period varying from 3-40 months (median 9.5 months). Selected asymptomatic patients with non-bulky disease may be suitable for no initial therapy. Randomized prospective trials will be needed to test whether survival is affected by delaying therapy.
Databáze: OpenAIRE