A report on a prospective trial of no initial therapy in patients with asymptomatic favourable prognosis non-Hodgkin's lymphoma
| Autor: | C. J. Williams, F. R. Macbeth, J. M. A. Whitehouse, R. D. H. Ryall, Graham M. Mead |
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| Rok vydání: | 1984 |
| Předmět: |
Cancer Research
Chemotherapy medicine.medical_specialty business.industry medicine.medical_treatment Hematology General Medicine Disease medicine.disease Asymptomatic Non-Hodgkin's lymphoma Lymphoma Surgery Oncology Internal medicine medicine medicine.symptom Stage (cooking) Prospective cohort study business Progressive disease |
| Zdroj: | Hematological Oncology. 2:179-188 |
| ISSN: | 0278-0232 |
| DOI: | 10.1002/hon.2900020207 |
| Popis: | Thirty-one (58 per cent) of a group of fifty-three unselected patients with stage II-IV favourable prognosis non-Hodgkin's lymphoma were regarded as being eligible for a prospective study of no initial therapy. Seventeen of these patients (55 per cent) have required no treatment for periods from 6 + -47 + months, (median 18 months) and fourteen patients have been treated with chemotherapy for progressive disease after a period varying from 3-40 months (median 9.5 months). Selected asymptomatic patients with non-bulky disease may be suitable for no initial therapy. Randomized prospective trials will be needed to test whether survival is affected by delaying therapy. |
| Databáze: | OpenAIRE |
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