Screening of some kenyan medicinal plants for antibacterial activity

Autor: Daniel Waweru Gakuya, F K Njonge, Mark Nanyingi, James K. Macharia, Anne Njuguna, Patrick Kareru, James M. Mbaria, Cyrus G. Wagate, Nduhiu Gitahi
Rok vydání: 2009
Předmět:
Zdroj: Phytotherapy Research. 24:150-153
ISSN: 0951-418X
DOI: 10.1002/ptr.2866
Popis: Eleven medicinal plants used by traditional healers in Machakos and Kitui District were screened, namely: Ajuga remota Benth, Aloe secundiflora Engl, Amaranthus hybridus L, Cassia didymobotrya Fes, Croton macrostachyus Del, Entada leptostachya Harms, Erythrina abyssinica DC, Harrisonia abyssinica Oliv, Schkuhria pinnata O. Ktze, Terminalia kilimandscharica Engl and Ziziphus abyssinica Hochst for potential antibacterial activity against four medically important bacterial strains, namely: Bacillus cereus ATCC 11778, Escherichia coli ATCC 25922, Micrococcus lutea ATCC 9341 and Pseudomonas aeruginosa ATCC 27853. The antibacterial activity of methanol extracts was determined as the minimum inhibitory concentration (MIC). The plant extracts were more active against Gram-positive (G+) than Gram-negative (G-) bacteria. The positive controls were streptomycin and benzylpenicillin for G- and G+ bacteria, respectively, both had a significant MIC at
Databáze: OpenAIRE