Metabolites of Marine Organisms as Regulators of O-Glycosylhydrolases

Autor:	Tatyana N. Zvyagintseva, Yu. V. Burtseva, N. S. Verigina, V. V. Sova, M. V. Pivkin, Svetlana P. Ermakova
Rok vydání:	2005
Předmět:	chemistry.chemical_classification biology Spisula sachalinensis Enzyme biosynthesis biology.organism_classification Applied Microbiology and Biotechnology Biochemistry Microbiology Brown algae chemistry.chemical_compound Sponge Enzyme Halichondriidae Biosynthesis chemistry Marine fungi
Zdroj:	Applied Biochemistry and Microbiology. 41:354-360
ISSN:	1608-3024 0003-6838
DOI:	10.1007/s10438-005-0060-2
Popis:	The ability of metabolites contained in culture liquid of 62 strains of marine fungi to affect the activity of two digestive enzymes of marine mollusks—endo-1,3-β-D-glucanase of Spisula sachalinensis and β-D-glucosidase of Littorina kurila—was studied. It was found that 66 and 71% of specimens activated, 18 and 7% inhibited, and 16 and 22% did not affect the activity of endo-1,3-β-D-glucanase and β-D-glucosidase, respectively. It is demonstrated that the metabolites of brown algae and marine sponges can be used for a targeted regulation of enzyme biosynthesis by marine fungi. The protein inhibitor of endo-1,3-β -D-glucanases isolated from the brown alga Laminaria cichorioides blocked the biosynthesis of almost all O-glycosylhydrolases in five strains of marine fungi studied. The presence in culture medium of halistanol sulfate from the marine sponge of the family Halichondriidae either did not affect or activated the biosynthesis of enzymes involved in carbohydrate metabolism by marine fungi.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c0c9024e61f50f3a088c53e510800467 https://doi.org/10.1007/s10438-005-0060-2 Zobrazit plný text záznamu Plný text ve formátu PDF