The Effect of Clonazepam Mouthwash on the Symptomatology of Burning Mouth Syndrome: An Open Pilot Study: Table 1
| Autor: | Luciano Alberto de Castro, Rejane Faria Ribeiro-Rotta |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
Dysesthesia business.industry General Medicine Burning mouth syndrome Dry mouth Dermatology Clonazepam Dysgeusia Clinical trial stomatognathic diseases Anesthesiology and Pain Medicine medicine.anatomical_structure Tongue Anesthesia medicine Neurology (clinical) medicine.symptom business Burning Sensation medicine.drug |
| Zdroj: | Pain Medicine. 15:2164-2166 |
| ISSN: | 1526-4637 1526-2375 |
| DOI: | 10.1111/pme.12552 |
| Popis: | Dear Editor, Burning mouth syndrome (BMS) is a chronic idiopathic disorder characterized by burning sensation or dysesthesia in the tongue and other oral sites without clinical and laboratory findings, often accompanied by dry mouth, tingling, or dysgeusia. There is no standard recognized treatment. Considering the peripheral nervous alterations identified in BMS patients, some clinical trials have demonstrated the efficacy of topical clonazepam on BMS symptoms [1,2]. This study aimed to investigate the effect of clonazepam mouthwash on BMS symptomatology. The efficacy of topical clonazepam has been demonstrated in previous studies [1,2] where the drug was administrated as a mouth dissolving tablet. In addition, recent findings from an experimental animal study [3] demonstrated the presence of GABA A receptors in the tongue nerve fibers of rats. As benzodiazepines bind to GABA A receptors, these findings support the … |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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