Efficient One-Pot Synthesis of Mono- and Bis[di(2-pyridyl)phosphine Oxides] from Tris(2-pyridyl)phosphine

Autor:	Alexander V. Artem'ev, Nina K. Gusarova, Svetlana F. Malysheva, Anastasiya O. Sutyrina, Yuriy I. Litvintsev, Irina V. Sterkhova, Alexander I. Albanov, Nataliya A. Belogorlova
Rok vydání:	2016
Předmět:	Tris 010405 organic chemistry Chemistry Organic Chemistry One-pot synthesis Halide 010402 general chemistry Alkali metal 01 natural sciences Medicinal chemistry 0104 chemical sciences chemistry.chemical_compound Organic chemistry Phosphonium Phosphine
Zdroj:	Synlett. 27:2451-2454
ISSN:	1437-2096 0936-5214
DOI:	10.1055/s-0035-1562485
Popis:	An efficient one-pot access to di(2-pyridyl)phosphine oxides Py2P(R)=O and bis[di(2-pyridyl)phosphine oxides] Py2P(O)–Z–P(O)Py2 has been developed based on the reaction of available tris(2-pyridyl)phosphine with various organic halides, followed by treatment of the resulting phosphonium salts with alkali in situ. The isolated yields of the phosphine oxides were in the range 40–96%.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c0ae79d88ab97c6736765e30f3f10304 https://doi.org/10.1055/s-0035-1562485 Zobrazit plný text záznamu